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Cambridge Centre for Medical Materials

Department of Materials Science and Metallurgy

Studying at Cambridge

 

Dr. Natalia Davidenko

Dr. Natalia Davidenko

Post-Doctoral Research Associate


Office Phone: +44 (0)1223 334560

Biography:

Russian by birth.  Obtained BSc and PhD from Moscow Lomonosov University, Russia.  Moved to Cuba in 1983 and worked until1991 as a researcher at Havana University.   In 1991 was joint founder of a new Centre for Biomaterials in Havana University, and assumed role as Head of Department of Macromolecular Chemistry for 18 years.  Travelled extensively to UK, Spain and many other countries as invited lecturer and researcher during this period.  Latterly, moved residence to UK (as British Citizen), and now lives permanently in Cambridge employed as Research Associate in the Cambridge Centre for Medical Materials of Cambridge University, UK.

Research Interests

Polymeric and composite materials for biomedical applications: bone cements, dental composites, biodegradable drug delivery systems and scaffolds for tissue engineering. Most significant achievements are related to the synthesis and characterization of polymeric hybrid systems with modulated biological responses (biostable and biodegradable) and to the design of biodegradable chitosan/synthetic polymer-based matrices for controlled drug delivery and hydroxyapatite-based nano-composites for in-situ bone regeneration. 

Resent research is focussed on the development of biomimetic, naturally derived, 3D models for tissue engineering applications, especially on the design of biodegradable collagen-base scaffolds with flexible environment tailored to specific cell phenotypes. Experimental work has been specifically related to all aspects of scaffold engineering for in-vitro modeling of mammary gland and to the design and preparation of collagen-based 3D models for heart tissue regeneration.

Key Publications

  • J.J. CAMPBELL, L. BOTOS, T.J. SARGEANT, N. DAVIDENKO, R.E. CAMERON and C.J. WATSON
    “A 3-D in vitro co-culture model of mammary gland involution”, Integr Biol, (2014)
    DOI: 10.1039/c3ib40257f, 2014.
  • J.V. ARAUJO, N. DAVIDENKO, M.DANNER, R.E. CAMERON and S.M. BEST
    “ Novel porous scaffolds of pH responsive chitosan/carrageenan-based polyelectrolyte complexes for tissue engineering”, J Biomed Mater Res Part A., (2014)
    DOI: 10.1002/jbm.a.35128,  2014.
  • N. DAVIDENKO,  T. GIBB, C. SCHUSTER, S.M. BEST, J.J. CAMPBELL,  C.J. WATSON and R.E. CAMERON
    “Biomimetic collagen scaffolds with anisotropic pore architecture”, Acta Biomaterialia, 8, 667-676, (2012)
  • J.J. CAMPBELL, N. DAVIDENKO, M.M.CAFFAREL, R.E. CAMERON and C.J. WATSON
    “A Multifunctional 3D Co-Culture System for Studies of Mammary Tissue Morphogenesis and Stem Cell Biology”, PLoS ONE, 6 (9), e25661, (2011)
  • N. DAVIDENKO, J.J. CAMPBELL, E.S. THIAN, C.J. WATSON and R.E. CAMERON
    “Collagen–hyaluronic acid scaffolds for adipose tissue engineering”, Acta Biomaterialia, 6, 3957–3968, (2010)
  • N. DAVIDENKO, R.GARCIA CARRODEGUAS, C. PENICHE, Y. SOLIS and R.E. CAMERON
    “Chitosan/apatite composite beads prepared by in situ generation of apatite or Si-apatite nanocrystals”, Acta Biomaterialia, 6, 466-476, (2010)