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Cambridge Centre for Medical Materials

Department of Materials Science and Metallurgy

Studying at Cambridge

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The main research areas of the group concern materials and biomaterials for use in the following applications,

  • Skeletal Implants
  • Medical Prostheses and Devices
  • Drug Delivery Systems
  • Tissue Engineering
  • Bio ceramics and Bioceramic/Bioactive Coatings
  • Resorbable and Stable Polymers for Implantation

 


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Highlighted Publications

J.H. SHEPHERD, D.HOWARD, A.K. WALLER, H.R. FOSTER, A. MUELLER, T. MOREAU, A.L. EVANS, M. ARUMUGAM, G. BOUËT CHALON, E. VRIEND, N. DAVIDENKO, C. GHEVAERT, S.M. BEST AND R.E. CAMERON “Structurally graduated collagen scaffolds applied to the ex vivo generation of platelets from human pluripotent stem cell-derived megakaryocytes: Enhancing production and purity”, Biomaterials, 182, 135 – 144 (2018) doi.org/10.1016/j.biomaterials.2018.08.019

R.D. HUME, S. PENSA, E.J. BROWN, P.A. KREUZALER, J. HITCHCOCK, A. HUSMANN, J.J. CAMPBELL, A.O. LLOYD-THOMAS, R.E. CAMERON AND C.J. WATSON “Tumour cell invasiveness and response to chemotherapeutics in adipocyte invested 3D engineered anisotropic collagen scaffolds”, Scientific Reports 8, 12658 (2018) doi.org/10.1038/s41598-018-30107-3

M. NAIR, A. HUSMANN, R E CAMERON and S BEST “In situ ESEM imaging of the vapor-pressure-dependent sublimation-induced morphology of ice”, Physical Review Materials 2, 2(4) (2018) 040401 doi: 10.1103/PhysRev Materials 2.040401

J.D. MALCOR, V. JUSKAITE, D. GAVRIILIDOU, E. HUNTER, N. DAVIDENKO, S. HAMAIA, S. SINHA, R.E. CAMERON, S.M. BEST, B. LEITINGER, R. FARNDALE “Coupling of a specific photoreactive triple-helical peptide to crosslinked collagen films restores binding and activation of DDR2 and VWF”, Biomaterials, 182, 21-34, (2018) doi: 10.1016/j.biomaterials.2018.07.050

J.C. ASHWORTH, M. MEHR, P.G. BUXTON, S.M. BEST AND R.E. CAMERON “Towards Cellular Sieving: Exploring the Limits of Scaffold Accessibility for Cell Type Specific Invasion”, Advanced Biosystems, 2, 1700257 (2018) doi.org/10.1002/adbi.201700257

D.V. SHEPHERD, J.H. SHEPHERD, S.M. BEST AND R.E. CAMERON “3D imaging of cells in scaffolds: direct labelling for micro CT”, Journal of Materials Science - Materials in Medicine, 29(6), 86, (2018) doi: 10.1103/PhysRev Materials 2.040401

R.D. HUME, L. BERRY, S. REICHELT, M. D’ANGELO, J. GOMM, R.E. CAMERON AND C.J. WATSON “An Engineered Human Adipose/Collagen Model for In Vitro Breast Cancer Cell Migration Studies”, Tissue Engineering Part A, 24,17-18 (2018) doi: 10.1089/ten.tea.2017.0509

G.S. OFFEDDU, C.E. TANASE, S. TOUMPANIARI, M.L. OYEN AND R.E. CAMERON “Stiffening by Osmotic Swelling Constraint in Cartilage‐Like Cell Culture Scaffolds”, Macromolecular Bioscience, 18, 1800247 (2018) doi: 10.1002/mabi.201800247

Z. AZHARI, S. McMAHON, L. PIERUCCI, W. WANG, R.E. CAMERON “Short poly(ethylene glycol) block initiation of poly(L-lactide) di-block copolymers: a strategy for tuning the degradation of resorbable devices”, Polymer International, 6, 726 – 738 (2018) doi: 10.1002/pi.5563

J.C. ASHWORTH, M.MEHR, P.G. BUXTON, S.M. BEST AND R.E. CAMERON “Optimising collagen scaffold architecture for enhanced periodontal ligament fibroblast migration”, Journal of Materials Science - Materials in Medicine, 29, 166 (2018) doi:.org/10.1007/s10856-018-6175-9

C.E. TANASE, M. GOLOZAR, S.M. BEST, R.A. BROOKS “Cell Response to Plasma Electrolytic Oxidation Surface-Modified Low-Modulus β-Type Titanium Alloys”, Colloids and Surfaces B: Biointerfaces, 176, 176-184 (2018)  doi.org/10.1016/j.colsurfb.2018.12.064

D.V.BAX, D.V. H.E. SMALLEY, R.W. FARNDALE, S.M. BEST, R.E. CAMERON “Cellular response to collagen-elastin composite materials”, Acta Biomaterialia, S1742-7061(18)30758-X (2018)  doi.org/10.1016/j.actbio.2018.12.033